Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866327 | 1.00 | NOTUM (0.43) | NOTUMCFTRSOS1KMT2AMEN1 | |
| SCHEMBL1448201 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31451989 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2152528 | 0.80 | ALDH1A1 (0.48) | CFTRKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13987139 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4196549 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22866318 | 0.78 | ALDH1A1 (0.44) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL15271018 | 0.78 | ALDH1A1 (0.47) | KMT2AMEN1HTTSMN1; SMN2GALR3 | |
| SCHEMBL6120101 | 0.78 | NOTUM (0.49) | NOTUMCFTRSOS1KMT2AMEN1 | |
| SCHEMBL22866081 | 0.77 | CFTR (0.52) | NOTUMCFTRSOS1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539855-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Borah, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244775-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-12-21 | — | — | WO | disclosed |