Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 6/20 | 0.80 |
| ▸ | LMNA | P02545 | 5/20 | 0.80 |
| ▸ | NPC1 | O15118 | 4/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31715954 | 0.89 | LMNA (1.00) | PLA2G2AALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL4009073 | 0.89 | LMNA (1.00) | PLA2G2AALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL4208879 | 0.88 | PLA2G2A (0.79) | PLA2G2AALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL31716926 | 0.87 | RAB9A (0.82) | PLA2G2AALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL28677971 | 0.86 | PLA2G2A (0.73) | PLA2G2AALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL2576382 | 0.86 | KDM4E (0.76) | PLA2G2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL16307495 | 0.84 | MAPT (0.74) | PLA2G2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL14970890 | 0.83 | CYP3A4 (0.78) | ALDH1A1KDM4ERAB9AHPGDLMNA | |
| SCHEMBL17923184 | 0.83 | MAPT (0.74) | PLA2G2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL28693800 | 0.83 | KDM4E (0.72) | PLA2G2AALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247351-A | Method for synthesizing nitrogen-containing heteroarene carboxylic acid compound based on hydrocarbon bond carboxylation reaction of nitrogen-containing heteroarene | 四川大学 | 2023-12-19 | — | — | CN | disclosed |