Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 7/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | TAF1 | P21675 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690767 | 0.90 | KIT (0.45) | KITULK1BTKWNT3A | |
| SCHEMBL30690690 | 0.87 | KIT (0.43) | KITULK1BTKWNT3A | |
| SCHEMBL30690482 | 0.86 | KIT (0.41) | KITULK1BTK | |
| SCHEMBL30690542 | 0.83 | KIT (0.39) | KITULK1BTKRAF1BRAF | |
| SCHEMBL30690666 | 0.83 | KIT (0.42) | KITCSF1RABL1 | |
| SCHEMBL30690660 | 0.80 | KIT (0.42) | KITCSF1RABL1 | |
| SCHEMBL30690513 | 0.80 | KIT (0.42) | KITCSF1RABL1 | |
| SCHEMBL30690501 | 0.79 | GSK3B (0.45) | KITCSF1RABL1 | |
| SCHEMBL30690716 | 0.79 | GSK3B (0.45) | KITCSF1RABL1 | |
| SCHEMBL30690504 | 0.79 | HRH3 (0.39) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |