Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 12/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 3/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690795 | 0.89 | ABL1 (0.43) | ALDH1A1HTTSMN1; SMN2L3MBTL1ABL1 | |
| SCHEMBL30690612 | 0.88 | GSK3B (0.47) | ABL1KITCSF1RWNT1GSK3B | |
| SCHEMBL30690514 | 0.87 | GSK3B (0.46) | ABL1KITCSF1RWNT1GSK3B | |
| SCHEMBL27280006 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2L3MBTL1ABL1 | |
| SCHEMBL30690544 | 0.86 | GSK3B (0.46) | KITWNT1GSK3BDYRK1A | |
| SCHEMBL30690480 | 0.85 | WNT1 (0.39) | ABL1KITCSF1RHDAC6WNT1 | |
| SCHEMBL30690725 | 0.85 | GSK3B (0.48) | SMN1; SMN2L3MBTL1ABL1KITCSF1R | |
| SCHEMBL30690606 | 0.85 | PDGFRA (0.41) | ABL1KITCSF1RWNT1CLK2 | |
| SCHEMBL30690481 | 0.85 | GSK3B (0.48) | ABL1KITCSF1RCCNA2CDK2 | |
| SCHEMBL30690695 | 0.85 | GSK3B (0.48) | SMN1; SMN2ABL1KITCSF1RWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |