Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.48 |
| ▸ | WNT1 | P04628 | 6/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 5/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690480 | 0.92 | WNT1 (0.39) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690553 | 0.92 | GSK3B (0.49) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690547 | 0.86 | GSK3B (0.46) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690544 | 0.86 | GSK3B (0.46) | GSK3BDYRK1AWNT1KIT | |
| SCHEMBL30690461 | 0.85 | WNT3A (0.42) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690703 | 0.85 | GSK3B (0.50) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690725 | 0.85 | GSK3B (0.48) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690674 | 0.85 | ALDH1A1 (0.42) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690717 | 0.84 | GSK3B (0.44) | GSK3BDYRK1AWNT1ABL1KIT | |
| SCHEMBL30690612 | 0.84 | GSK3B (0.47) | GSK3BDYRK1AWNT1ABL1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |