Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | WNT1 | P04628 | 3/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 4/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690431 | 1.00 | GSK3B (0.38) | GSK3BDYRK1AWNT1CCNA2CDK2 | |
| SCHEMBL30690695 | 0.90 | GSK3B (0.48) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690562 | 0.85 | GSK3B (0.45) | GSK3BDYRK1AWNT1CCNA2CDK2 | |
| SCHEMBL30690662 | 0.85 | GSK3B (0.45) | GSK3BDYRK1AWNT1CCNA2CDK2 | |
| SCHEMBL30690612 | 0.84 | GSK3B (0.47) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690703 | 0.82 | GSK3B (0.50) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690548 | 0.82 | GSK3B (0.49) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690664 | 0.82 | GSK3B (0.49) | GSK3BDYRK1AWNT1KITABL1 | |
| SCHEMBL30690674 | 0.82 | ALDH1A1 (0.42) | GSK3BDYRK1AWNT1CCNA2CDK2 | |
| SCHEMBL30690544 | 0.82 | GSK3B (0.46) | GSK3BDYRK1AWNT1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |