Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690687 | 0.89 | PIK3CA (0.32) | ABL1MTORHDAC3HDAC1HDAC2 | |
| SCHEMBL30690780 | 0.87 | HDAC3 (0.34) | ABL1BTKHDAC3HDAC1HDAC2 | |
| SCHEMBL30690642 | 0.84 | CSF1R (0.41) | ABL1HDAC3HDAC1HDAC2CD274 | |
| SCHEMBL30690765 | 0.84 | HRH3 (0.34) | HDAC3HDAC1HDAC2 | |
| SCHEMBL30690792 | 0.79 | PIK3CD (0.34) | MTORPIK3CDPIK3CA | |
| SCHEMBL30690811 | 0.77 | DYRK1A (0.38) | ABL1HDAC3HDAC1HDAC2CD274 | |
| SCHEMBL30690639 | 0.76 | GSK3B (0.38) | ABL1BTKHDAC3HDAC1HDAC2 | |
| SCHEMBL30690789 | 0.75 | BRAF (0.38) | HDAC3HDAC1 | |
| SCHEMBL30690647 | 0.74 | DYRK1A (0.41) | CD274 | |
| SCHEMBL30690835 | 0.73 | HDAC1 (0.36) | HDAC3HDAC1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |