⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30691702 | 0.83 | — | — | |
| SCHEMBL30691832 | 0.78 | DPP4 (0.33) | — | |
| SCHEMBL30691799 | 0.73 | — | — | |
| SCHEMBL30691036 | 0.72 | — | — | |
| SCHEMBL30691524 | 0.70 | DPP4 (0.33) | — | |
| SCHEMBL30691149 | 0.70 | DPP4 (0.33) | — | |
| SCHEMBL30691280 | 0.70 | MCHR1 (0.33) | — | |
| SCHEMBL30691607 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL30691530 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL30691590 | 0.65 | NQO2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119997954-A | Compounds for the treatment of spinocerebellar ataxia type 3 | PTC医疗公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4543444-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250316-A1 | COMPOUNDS FOR TREATING SPINOCEREBELLAR ATAXIA TYPE 3 | PTC THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |