Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 14/20 | 0.80 |
| ▸ | STK39 | Q9UEW8 | 6/20 | 0.75 |
| ▸ | PARG | Q86W56 | 1/20 | 0.75 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24438299 | 1.00 | PNLIP (0.80) | PNLIPSTK39PARGTMPRSS4 | |
| SCHEMBL24438027 | 0.93 | PNLIP (0.82) | PNLIPSTK39 | |
| SCHEMBL29655162 | 0.93 | PNLIP (0.82) | PNLIPSTK39 | |
| SCHEMBL30692674 | 0.87 | PNLIP (0.79) | PNLIPSTK39PARG | |
| SCHEMBL24438298 | 0.87 | PNLIP (0.79) | PNLIPSTK39PARG | |
| SCHEMBL23685789 | 0.87 | PNLIP (1.00) | PNLIPSTK39PARG | |
| SCHEMBL30692667 | 0.86 | TMPRSS4 (0.76) | PNLIPSTK39PARGTMPRSS4 | |
| SCHEMBL24438295 | 0.86 | TMPRSS4 (0.76) | PNLIPSTK39PARGTMPRSS4 | |
| SCHEMBL23685884 | 0.84 | PNLIP (0.83) | PNLIPSTK39 | |
| SCHEMBL18341186 | 0.83 | LRRK2 (0.60) | PNLIPSTK39PARGTMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230406831-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | THE TRUSTEES OF INDIANA UNIVERSITY | 2023-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230406831-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | HSP90B1, HSPBP1, HSP90AB1 | PNLIP 841/4885STK39 3354/4885PARG 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.