Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.76 |
| ▸ | PNLIP | P16233 | 6/20 | 0.73 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.71 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.70 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.60 |
| ▸ | PARG | Q86W56 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24438295 | 1.00 | TMPRSS4 (0.76) | TMPRSS4PNLIPP2RX1STK39P2RX4 | |
| SCHEMBL30692660 | 0.93 | P2RX1 (0.82) | TMPRSS4PNLIPP2RX1STK39P2RX4 | |
| SCHEMBL24438051 | 0.93 | P2RX1 (0.82) | TMPRSS4PNLIPP2RX1STK39P2RX4 | |
| SCHEMBL538439 | 0.87 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7KCNMA1 | |
| SCHEMBL30692665 | 0.86 | PNLIP (0.80) | TMPRSS4PNLIPSTK39PARG | |
| SCHEMBL24438299 | 0.86 | PNLIP (0.80) | TMPRSS4PNLIPSTK39PARG | |
| SCHEMBL29024720 | 0.85 | TMPRSS4 (0.83) | TMPRSS4P2RX1P2RX4P2RX7KCNMA1 | |
| SCHEMBL2169619 | 0.84 | P2RX1 (1.00) | TMPRSS4P2RX1P2RX4P2RX7KCNMA1 | |
| SCHEMBL29454776 | 0.84 | P2RX1 (1.00) | TMPRSS4P2RX1P2RX4P2RX7KCNMA1 | |
| SCHEMBL24438058 | 0.84 | TMPRSS4 (0.67) | TMPRSS4PNLIPP2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230406831-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | THE TRUSTEES OF INDIANA UNIVERSITY | 2023-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230406831-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | HSP90B1, HSPBP1, HSP90AB1 | TMPRSS4 3530/4885PNLIP 841/4885P2RX1 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.