Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30697146 | 0.83 | MPO (0.46) | MEN1KMT2ARXFP1CYP1A2CYP2C19 | |
| SCHEMBL30697035 | 0.76 | PTGER1 (0.56) | CYP1A2CYP2C19 | |
| SCHEMBL29276700 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2ARXFP1CYP1A2CYP2C19 | |
| SCHEMBL1520180 | 0.71 | HTT (0.64) | MEN1KMT2ARXFP1CYP1A2CYP2C19 | |
| SCHEMBL1008523 | 0.71 | HTT (0.68) | MEN1KMT2ARXFP1CYP1A2CYP2C19 | |
| SCHEMBL535668 | 0.70 | L3MBTL1 (0.58) | KMT2ACYP1A2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2760500 | 0.70 | HTT (0.70) | MEN1KMT2ARXFP1CYP1A2CYP2C19 | |
| SCHEMBL21678221 | 0.70 | L3MBTL1 (0.54) | KMT2ACYP1A2ALDH1A1HTTPOLB | |
| SCHEMBL28677368 | 0.69 | L3MBTL1 (0.57) | MEN1KMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL21245001 | 0.69 | ALDH1A1 (0.64) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451961-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 广州科恩泰生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-117186098-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |