Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.58 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252378 | 1.00 | P2RX1 (0.58) | P2RX1P2RX4P2RX7TMPRSS4PTGS1 | |
| SCHEMBL11791152 | 0.82 | P2RX1 (0.55) | P2RX1P2RX4P2RX7TMPRSS4PTGS1 | |
| SCHEMBL28091035 | 0.82 | GPR27 (0.57) | TMPRSS4MAPK1NPC1RAB9AMEN1 | |
| SCHEMBL6891415 | 0.81 | P2RX1 (0.68) | P2RX1P2RX4P2RX7TMPRSS4PTGS1 | |
| SCHEMBL14000601 | 0.78 | P2RX1 (0.48) | P2RX1P2RX4P2RX7TMPRSS4PTGS1 | |
| SCHEMBL330564 | 0.77 | P2RX1 (0.76) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL28596892 | 0.75 | FADS1 (0.71) | P2RX1P2RX4P2RX7TMPRSS4MAPK1 | |
| SCHEMBL330755 | 0.73 | FADS1 (0.77) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL332057 | 0.73 | P2RX1 (1.00) | P2RX1P2RX4P2RX7TMPRSS4MEN1 | |
| SCHEMBL11798950 | 0.72 | TMPRSS4 (0.51) | P2RX1P2RX4P2RX7TMPRSS4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038563-A1 | SYSTEMS AND METHODS FOR COLD HYPERSENSITIVITY ASSESSMENTS AS AN INDICATOR FOR CIPN | WASHINGTON UNIVERSITY (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-117512016-A | Method for constructing COL3A1 transgenic zebra fish as carrier to express human type III collagen | 福州大学 | 2024-02-06 | — | — | CN | disclosed |