Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.58 |
| ▸ | BCHE | P06276 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | SNCA | P37840 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30697368 | 0.90 | NOX1 (0.62) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL7673182 | 0.90 | NOX1 (0.62) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL4706434 | 0.89 | NOX1 (0.68) | NOX1BCHEACHEMAPTGAA | |
| Hydrochloric Acid SCHEMBL20495637 | 0.88 | NOX1 (0.60) | NOX1BCHEACHEMAPTGAA | |
| Hydrochloric Acid SCHEMBL30448208 | 0.88 | NOX1 (0.60) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL28117917 | 0.86 | NOX1 (0.76) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL4706870 | 0.85 | NOX1 (0.45) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL239261 | 0.81 | NOX1 (0.79) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL30769670 | 0.81 | NOX1 (0.79) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL1855994 | 0.79 | NOX1 (0.65) | NOX1BCHEACHEMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765797-A4 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | UNIV KANSAS CT FOR RES INC (US) | 2008-02-06 | — | — | EP | claimed |
| EP-1765797-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | University of Kansas Center for Research, Inc. (US) | 2007-03-28 | — | — | EP | claimed |
| WO-2006002441-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | UNIVERSITY OF KANSAS (US) | 2006-01-05 | — | — | WO | claimed |
| US-20050288279-A1 | Phenothiazine derivatives and their method of use | KANSAS MEDICAL CENTER, UNIVERSITY OF | 2005-12-29 | — | — | US | claimed |
| EP-1765797-A4 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | UNIV KANSAS CT FOR RES INC (US) | 2008-02-06 | — | — | EP | disclosed |
| EP-1765797-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | University of Kansas Center for Research, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006002441-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | UNIVERSITY OF KANSAS (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050288279-A1 | Phenothiazine derivatives and their method of use | KANSAS MEDICAL CENTER, UNIVERSITY OF | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288279-A1 | Phenothiazine derivatives and their method of use | SHBG, GPR119, BRDT | NOX1 3177/4885BCHE 3057/4885ACHE 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.