Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081903 | 0.83 | MAPK1 (0.59) | GPR88 | |
| SCHEMBL22548740 | 0.82 | MAPK1 (0.48) | — | |
| SCHEMBL30697672 | 0.81 | GAA (0.59) | GPR88 | |
| SCHEMBL8084860 | 0.79 | RARB (0.59) | GPR88 | |
| SCHEMBL10804900 | 0.79 | TSHR (0.48) | GPR88 | |
| SCHEMBL10804894 | 0.79 | TSHR (0.48) | GPR88 | |
| SCHEMBL10029313 | 0.78 | L3MBTL1 (0.60) | — | |
| SCHEMBL13543186 | 0.77 | PARP10 (0.61) | — | |
| SCHEMBL8080346 | 0.77 | KDM4E (0.53) | GPR88 | |
| SCHEMBL8072216 | 0.77 | GPR88 (0.49) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543857-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA Pharmaceuticals Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250060-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. (US) | 2023-12-28 | — | — | WO | disclosed |