Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699586 | 0.77 | — | — | |
| SCHEMBL29091632 | 0.75 | CYP19A1 (0.32) | APPPDGFRBPDGFRACYP1A2 | |
| SCHEMBL30699478 | 0.75 | KDM1A (0.40) | — | |
| SCHEMBL31491045 | 0.74 | — | — | |
| SCHEMBL10754460 | 0.73 | ALDH1A1 (0.36) | PDGFRBCYP1A2 | |
| SCHEMBL25328584 | 0.70 | ALDH1A1 (0.41) | APP | |
| SCHEMBL27295502 | 0.70 | APP (0.34) | APPCYP1A2 | |
| SCHEMBL31490996 | 0.69 | — | — | |
| SCHEMBL29091591 | 0.69 | YTHDC1 (0.32) | APPCYP1A2 | |
| SCHEMBL16689327 | 0.68 | SMN1; SMN2 (0.41) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244713-A1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |