Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699948 | 0.90 | MGLL (0.43) | MGLLTEAD1MCHR1USP2PKM | |
| SCHEMBL30700223 | 0.82 | MGLL (0.39) | MGLLENPP2ATXN2TEAD1MCHR1 | |
| SCHEMBL30700204 | 0.82 | MGLL (0.39) | MGLLENPP2ATXN2TEAD1MCHR1 | |
| SCHEMBL25324564 | 0.79 | ENPP2 (0.38) | MGLLENPP2ATXN2PDCD1LG2CD274 | |
| SCHEMBL30699918 | 0.79 | MGLL (0.41) | MGLLTEAD1MCHR1USP2PKM | |
| SCHEMBL30700088 | 0.79 | MGLL (0.41) | MGLLTEAD1MCHR1USP2PKM | |
| SCHEMBL30700153 | 0.78 | MGLL (0.44) | MGLLENPP2ATXN2 | |
| SCHEMBL30700507 | 0.78 | MGLL (0.44) | MGLLENPP2ATXN2 | |
| SCHEMBL30700903 | 0.78 | MGLL (0.40) | MGLLENPP2ATXN2USP2PKM | |
| SCHEMBL30700687 | 0.77 | MCHR1 (0.43) | MGLLMCHR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |