Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699918 | 1.00 | MGLL (0.41) | MGLLTEAD1MCHR1IDO1ALDH1A1 | |
| SCHEMBL30700502 | 0.91 | TEAD1 (0.39) | MGLLTEAD1MCHR1IDO1SCN9A | |
| SCHEMBL30699948 | 0.88 | MGLL (0.43) | MGLLTEAD1MCHR1ALDH1A1LMNA | |
| SCHEMBL30700033 | 0.87 | TACR1 (0.38) | MCHR1F2R | |
| SCHEMBL30700165 | 0.84 | MCHR1 (0.41) | MGLLMCHR1 | |
| SCHEMBL30700175 | 0.82 | KCNH2 (0.41) | TEAD1 | |
| SCHEMBL30700669 | 0.82 | MGLL (0.41) | MGLLMCHR1IDO1ALDH1A1LMNA | |
| SCHEMBL30699889 | 0.82 | FAAH (0.41) | — | |
| SCHEMBL30700903 | 0.81 | MGLL (0.40) | MGLLIDO1ALDH1A1LMNAPKM | |
| SCHEMBL30699915 | 0.81 | TEAD1 (0.41) | TEAD1MCHR1IDO1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |