Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 9/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | DLK1 | P80370 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323631 | 0.91 | MGLL (0.42) | MGLLPIM1BTKFFAR4HCRTR1 | |
| SCHEMBL30700373 | 0.87 | MGLL (0.43) | MGLLPIM1HCRTR1 | |
| SCHEMBL30700423 | 0.87 | MGLL (0.44) | MGLLPIM1BTK | |
| SCHEMBL30700516 | 0.85 | MGLL (0.44) | MGLLPIM1MAP3K12 | |
| SCHEMBL30700859 | 0.84 | MGLL (0.40) | MGLLPIM1BTKFFAR4 | |
| SCHEMBL30700098 | 0.84 | MGLL (0.42) | MGLLPIM1 | |
| SCHEMBL30700274 | 0.84 | MGLL (0.41) | MGLLPIM1 | |
| SCHEMBL30700358 | 0.84 | MGLL (0.41) | MGLLPIM1 | |
| SCHEMBL30700591 | 0.84 | MGLL (0.40) | MGLLPIM1BTKMAP3K12 | |
| SCHEMBL30700187 | 0.83 | MGLL (0.43) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |