Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | LCAT | P04180 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.31 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699890 | 0.93 | MGLL (0.41) | MGLLPIM1KCNH2GRIN2BKCNQ3 | |
| SCHEMBL30553237 | 0.92 | MGLL (0.42) | MGLLPAK1PIM1KCNH2GRIN2B | |
| SCHEMBL25325537 | 0.92 | MGLL (0.42) | MGLLPAK1PIM1KCNH2GRIN2B | |
| SCHEMBL30700516 | 0.88 | MGLL (0.44) | MGLLPAK1PIM1LCAT | |
| SCHEMBL30700423 | 0.87 | MGLL (0.44) | MGLLPAK1PIM1 | |
| SCHEMBL30700098 | 0.86 | MGLL (0.42) | MGLLPAK1PIM1KCNH2 | |
| SCHEMBL30700373 | 0.86 | MGLL (0.43) | MGLLPAK1PIM1LCAT | |
| SCHEMBL30700859 | 0.85 | MGLL (0.40) | MGLLPAK1PIM1 | |
| SCHEMBL30700357 | 0.84 | MGLL (0.41) | MGLLPIM1 | |
| SCHEMBL30700348 | 0.82 | MGLL (0.44) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |