Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700165 | 0.88 | MCHR1 (0.41) | MGLLSLC6A4MCHR1SLC6A2SLC6A3 | |
| SCHEMBL30699918 | 0.82 | MGLL (0.41) | MGLLMCHR1IDO1ALDH1A1LMNA | |
| SCHEMBL30700088 | 0.82 | MGLL (0.41) | MGLLMCHR1IDO1ALDH1A1LMNA | |
| SCHEMBL30700903 | 0.80 | MGLL (0.40) | MGLLIDO1ALDH1A1LMNAGPR119 | |
| SCHEMBL30700502 | 0.76 | TEAD1 (0.39) | MGLLMCHR1IDO1KCNH2 | |
| SCHEMBL30700687 | 0.75 | MCHR1 (0.43) | MGLLSLC6A4MCHR1SLC6A2SLC6A3 | |
| SCHEMBL25325509 | 0.73 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3LTC4SHTR2A | |
| SCHEMBL25324718 | 0.72 | SLC6A4 (0.40) | MGLLSLC6A4MCHR1SLC6A2SLC6A3 | |
| SCHEMBL30700163 | 0.72 | MGLL (0.42) | MGLLSLC6A4MCHR1SLC6A2SLC6A3 | |
| SCHEMBL30699948 | 0.71 | MGLL (0.43) | MGLLMCHR1ALDH1A1LMNARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |