Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700088 | 0.91 | MGLL (0.41) | TEAD1MCHR1IDO1MGLLSCN9A | |
| SCHEMBL30699918 | 0.91 | MGLL (0.41) | TEAD1MCHR1IDO1MGLLSCN9A | |
| SCHEMBL30699889 | 0.85 | FAAH (0.41) | FAAHP2RX7 | |
| SCHEMBL30699915 | 0.84 | TEAD1 (0.41) | TEAD1FAAHMCHR1IDO1CYP2D6 | |
| SCHEMBL30700033 | 0.80 | TACR1 (0.38) | MCHR1P2RX7 | |
| SCHEMBL30699948 | 0.79 | MGLL (0.43) | TEAD1MCHR1MGLLSCN9A | |
| SCHEMBL30700175 | 0.79 | KCNH2 (0.41) | TEAD1P2RX7KCNH2 | |
| SCHEMBL30700165 | 0.78 | MCHR1 (0.41) | FAAHMCHR1MGLLKCNH2 | |
| SCHEMBL30700669 | 0.76 | MGLL (0.41) | MCHR1IDO1MGLLKCNH2 | |
| SCHEMBL30700903 | 0.75 | MGLL (0.40) | FAAHIDO1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |