Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | TGM1 | P22735 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326087 | 1.00 | ACACB (0.37) | ACACBEIF2AK4F13A1TGM2TGM1 | |
| SCHEMBL25261806 | 0.89 | ACACB (0.38) | ACACBEIF2AK4F13A1TGM2TGM1 | |
| SCHEMBL31308707 | 0.85 | GPR119 (0.37) | ACACBEIF2AK4F13A1TGM2TGM1 | |
| SCHEMBL25260156 | 0.85 | GPR119 (0.37) | ACACBEIF2AK4F13A1TGM2TGM1 | |
| SCHEMBL25299042 | 0.82 | GPR119 (0.38) | ACACBEIF2AK4F13A1TGM2TGM1 | |
| SCHEMBL31365772 | 0.82 | GPR119 (0.38) | ACACBEIF2AK4F13A1TGM2TGM1 | |
| SCHEMBL31308716 | 0.82 | F13A1 (0.41) | ACACBF13A1TGM2TGM1GPR119 | |
| SCHEMBL30700686 | 0.82 | F13A1 (0.41) | ACACBF13A1TGM2TGM1GPR119 | |
| SCHEMBL30700746 | 0.82 | GPR119 (0.36) | ACACBEIF2AK4CYP11B2GPR119 | |
| SCHEMBL25294482 | 0.81 | EIF2AK4 (0.40) | ACACBEIF2AK4NR1H2CYP11B2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568972-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| CN-119654326-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2024033277-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |