Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25299042 | 1.00 | GPR119 (0.38) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL25291423 | 0.83 | USP2 (0.31) | — | |
| SCHEMBL31308707 | 0.83 | GPR119 (0.37) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL25260156 | 0.83 | GPR119 (0.37) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL25326087 | 0.82 | ACACB (0.37) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL30700685 | 0.82 | ACACB (0.37) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL26631451 | 0.82 | ACACB (0.38) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL25411224 | 0.81 | GPR119 (0.39) | GPR119SCD5HDAC4CYP11B2ACACB | |
| SCHEMBL31308716 | 0.80 | F13A1 (0.41) | GPR119SCD5ACACBRORCF13A1 | |
| SCHEMBL30700686 | 0.80 | F13A1 (0.41) | GPR119SCD5ACACBRORCF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654326-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2025-03-18 | — | — | CN | disclosed |