Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | TGM1 | P22735 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31308716 | 1.00 | F13A1 (0.41) | F13A1TGM2TGM1JAK2JAK1 | |
| SCHEMBL30700782 | 0.85 | JAK2 (0.40) | F13A1TGM2TGM1JAK2JAK1 | |
| SCHEMBL25326087 | 0.82 | ACACB (0.37) | F13A1TGM2TGM1JAK2JAK1 | |
| SCHEMBL30700685 | 0.82 | ACACB (0.37) | F13A1TGM2TGM1JAK2JAK1 | |
| SCHEMBL25325917 | 0.82 | ACACB (0.36) | F13A1TGM2TGM1GPR119ACACB | |
| SCHEMBL30553426 | 0.82 | ACACB (0.36) | F13A1TGM2TGM1GPR119ACACB | |
| SCHEMBL25299042 | 0.80 | GPR119 (0.38) | F13A1TGM2TGM1GPR119ACACB | |
| SCHEMBL31365772 | 0.80 | GPR119 (0.38) | F13A1TGM2TGM1GPR119ACACB | |
| SCHEMBL25294350 | 0.80 | RORC (0.38) | JAK2JAK1GPR119SCD5RORC | |
| SCHEMBL29497035 | 0.80 | RORC (0.38) | JAK2JAK1GPR119SCD5RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |