Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.38 |
| ▸ | LCAT | P04180 | 2/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700419 | 1.00 | MGLL (0.38) | MGLLLCATEGLN2EGLN1EGLN3 | |
| SCHEMBL30700334 | 0.95 | MGLL (0.36) | MGLLLCATEGLN2EGLN1EGLN3 | |
| SCHEMBL30700187 | 0.94 | MGLL (0.43) | MGLLLCATEGLN2EGLN1EGLN3 | |
| SCHEMBL30699952 | 0.89 | MGLL (0.38) | MGLL | |
| SCHEMBL30700138 | 0.83 | GPR119 (0.36) | MGLL | |
| SCHEMBL30700427 | 0.83 | MGLL (0.42) | MGLL | |
| SCHEMBL30700373 | 0.82 | MGLL (0.43) | MGLLLCAT | |
| SCHEMBL30700274 | 0.82 | MGLL (0.41) | MGLL | |
| SCHEMBL27373057 | 0.80 | MGLL (0.47) | MGLL | |
| SCHEMBL27373058 | 0.80 | MGLL (0.47) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |