Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700127 | 0.89 | MGLL (0.42) | MGLLFAAHPIK3CDPIK3R1 | |
| SCHEMBL30700053 | 0.85 | MGLL (0.40) | MGLLFAAHPIK3CD | |
| SCHEMBL30700110 | 0.83 | ENPP2 (0.39) | MGLLPIK3CDPIK3R1 | |
| SCHEMBL30700437 | 0.81 | MGLL (0.40) | MGLLFAAHPIK3CDPIK3R1 | |
| SCHEMBL30700845 | 0.79 | TRPC6 (0.39) | MGLL | |
| SCHEMBL30700301 | 0.79 | MGLL (0.44) | MGLLFAAH | |
| SCHEMBL30700259 | 0.77 | ENPP2 (0.39) | PIK3CDPIK3R1 | |
| SCHEMBL27291240 | 0.75 | MGLL (0.36) | MGLL | |
| SCHEMBL30700018 | 0.75 | ENPP2 (0.39) | MGLLPIK3CDPIK3R1 | |
| SCHEMBL30700337 | 0.75 | SCN9A (0.33) | FAAHPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |