Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325147 | 0.86 | DDB1 (0.46) | NAMPTRORCTACR1PDE4B | |
| SCHEMBL30721151 | 0.86 | DDB1 (0.46) | NAMPTRORCTACR1PDE4B | |
| SCHEMBL29496971 | 0.84 | DDB1 (0.39) | RORCMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL25295844 | 0.84 | DDB1 (0.39) | RORCMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL21382579 | 0.83 | LIPE (0.43) | NAMPTRORCTACR1GPR119 | |
| SCHEMBL30700821 | 0.83 | NAMPT (0.45) | NAMPTRORCMAPTTACR1PDE4B | |
| SCHEMBL25292199 | 0.79 | GPR119 (0.38) | NAMPTRORCGPR119KDM4E | |
| SCHEMBL21381654 | 0.78 | RORC (0.46) | RORCTACR1PDE4BKDM4E | |
| SCHEMBL25327834 | 0.76 | RORC (0.47) | NAMPTRORCTACR1PDE4BKDM4E | |
| SCHEMBL22059421 | 0.76 | RORC (0.57) | RORCMAPTTACR1GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |