Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438282 | 0.81 | GPR119 (0.47) | GPR119L3MBTL1IDO1CYP1A2CYP3A4 | |
| SCHEMBL30701033 | 0.78 | BUB1 (0.43) | GPR119MAPK1PARP1TNKS2PARP2 | |
| SCHEMBL24001751 | 0.75 | UCHL1 (0.45) | MAPK1HDAC1HDAC6PARP1TNKS2 | |
| SCHEMBL31330330 | 0.75 | STS (0.40) | MEN1KMT2AHDAC1HDAC6PARP1 | |
| SCHEMBL29814869 | 0.74 | MAP4K1 (0.39) | UCHL1BUB1 | |
| SCHEMBL4698629 | 0.72 | HDAC1 (0.46) | ALDH1A1MAPK1KMT2AHDAC1HDAC6 | |
| SCHEMBL21605189 | 0.71 | SMN1; SMN2 (0.45) | MEN1ALDH1A1MAPTKMT2ASCN5A | |
| SCHEMBL18789182 | 0.71 | POLB (0.44) | GPR119MEN1MAPK1KMT2AHDAC1 | |
| SCHEMBL18387611 | 0.70 | UCHL1 (0.70) | GPR119UCHL1 | |
| SCHEMBL28717965 | 0.70 | UCHL1 (0.70) | GPR119UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |