Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150570 | 0.81 | BUB1 (0.43) | BUB1GPR119UCHL1PIK3CAMTOR | |
| SCHEMBL29845321 | 0.80 | DHPS (0.45) | UCHL1PIK3CADHPS | |
| SCHEMBL24001751 | 0.80 | UCHL1 (0.45) | BUB1UCHL1PARP1TNKS2PARP2 | |
| SCHEMBL31330330 | 0.80 | STS (0.40) | BUB1PARP1TNKS2PARP2PIM1 | |
| SCHEMBL30700998 | 0.78 | GPR119 (0.40) | BUB1GPR119UCHL1PIK3CAMTOR | |
| SCHEMBL29814869 | 0.77 | MAP4K1 (0.39) | BUB1UCHL1 | |
| SCHEMBL18789182 | 0.75 | POLB (0.44) | BUB1GPR119PIK3CAMTORUSP30 | |
| SCHEMBL29814515 | 0.74 | PIK3CA (0.42) | BUB1GPR119PIK3CAMTORMAPK1 | |
| SCHEMBL29879205 | 0.74 | RET (0.38) | PARP1TNKS2PARP2PIM1PIM2 | |
| SCHEMBL23771943 | 0.73 | KDM4E (0.51) | PIK3CAMTORPDK4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |