Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494900 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPK1LMNAHTTHSD17B10 | |
| SCHEMBL12341859 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNAHTTTDP1 | |
| SCHEMBL27610923 | 0.81 | ALDH1A1 (0.32) | ALDH1A1MAPK1LMNAHTTMEN1 | |
| SCHEMBL28072926 | 0.79 | TSHR (0.50) | ALDH1A1MAPK1LMNAHTTHSD17B10 | |
| SCHEMBL31093806 | 0.79 | TSHR (0.50) | ALDH1A1MAPK1LMNAHTTHSD17B10 | |
| SCHEMBL4351783 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNAHTTTDP1 | |
| SCHEMBL27629941 | 0.76 | DGAT1 (0.41) | ALDH1A1LMNASMN1; SMN2VCAM1MEN1 | |
| SCHEMBL1473281 | 0.76 | TDP1 (0.56) | ALDH1A1MAPK1LMNAHTTHSD17B10 | |
| SCHEMBL8159027 | 0.76 | GPR35 (0.52) | ALDH1A1MAPK1HSD17B10TDP1TSHR | |
| SCHEMBL541960 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |