Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.68 |
| ▸ | MAOB | P27338 | 10/20 | 0.68 |
| ▸ | HTR5A | P47898 | 6/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | DRD5 | P21918 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133417 | 1.00 | MAOA (0.68) | MAOAMAOBHTR5ADRD2HTR1A | |
| SCHEMBL15601712 | 0.81 | MAOA (1.00) | MAOAMAOBDRD2 | |
| SCHEMBL29133426 | 0.81 | HTR5A (0.65) | HTR5A | |
| SCHEMBL30704343 | 0.80 | HTR5A (0.64) | HTR5ADRD2HTR1ADRD1DRD4 | |
| SCHEMBL20078437 | 0.80 | MAOA (0.98) | MAOAMAOBDRD2 | |
| SCHEMBL30704344 | 0.79 | HTR5A (0.61) | HTR5ADRD2HTR1ADRD1DRD4 | |
| SCHEMBL29133409 | 0.79 | HTR5A (0.64) | MAOAMAOBHTR5ADRD2DRD3 | |
| SCHEMBL30704357 | 0.79 | HTR5A (0.64) | MAOAMAOBHTR5ADRD2DRD3 | |
| SCHEMBL16559664 | 0.78 | MAOA (1.00) | MAOAMAOBDRD2 | |
| SCHEMBL25570556 | 0.78 | MAOA (0.83) | MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |