Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 9/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704357 | 1.00 | HTR5A (0.64) | HTR5ADRD2DRD3MAOBMAOA | |
| SCHEMBL30704356 | 0.89 | HTR5A (0.61) | HTR5ADRD2DRD3MAOB | |
| SCHEMBL29133438 | 0.89 | HTR5A (0.61) | HTR5ADRD2DRD3MAOB | |
| SCHEMBL30704343 | 0.84 | HTR5A (0.64) | HTR5ADRD2DRD3 | |
| SCHEMBL30704344 | 0.82 | HTR5A (0.61) | HTR5ADRD2DRD3 | |
| SCHEMBL29133426 | 0.81 | HTR5A (0.65) | HTR5A | |
| SCHEMBL30704360 | 0.79 | HTR5A (0.65) | HTR5A | |
| SCHEMBL30704377 | 0.79 | HTR5A (0.56) | HTR5ADRD2 | |
| SCHEMBL29133431 | 0.79 | HTR5A (0.56) | HTR5ADRD2 | |
| SCHEMBL30704366 | 0.79 | MAOA (0.68) | HTR5ADRD2DRD3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |