Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226331 | 1.00 | PDE3B (0.50) | PDE3BPDE3AGAAPKMALDH1A1 | |
| SCHEMBL17434450 | 0.79 | CA12 (0.54) | PDE3BPDE3AGAAALDH1A1KDM4E | |
| SCHEMBL16198465 | 0.76 | ALDH1A1 (0.56) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL22424899 | 0.74 | MAPT (0.68) | GAAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21927159 | 0.72 | AURKA (0.47) | PDE3BPDE3AGAAALDH1A1KDM4E | |
| SCHEMBL22425308 | 0.72 | MAPT (0.63) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL22424889 | 0.72 | MAPT (0.60) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL13293335 | 0.71 | GAA (0.48) | PDE3BPDE3AGAAPKMALDH1A1 | |
| SCHEMBL92048 | 0.71 | GAA (0.53) | PDE3BPDE3AGAAPKMKDM4E | |
| SCHEMBL3348374 | 0.71 | GAA (0.48) | PDE3BPDE3AGAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |