Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704392 | 1.00 | PDE3B (0.50) | PDE3BPDE3AGAAPKMALDH1A1 | |
| SCHEMBL17434450 | 0.79 | CA12 (0.54) | PDE3BPDE3AGAAALDH1A1KDM4E | |
| SCHEMBL16198465 | 0.76 | ALDH1A1 (0.56) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL22424899 | 0.74 | MAPT (0.68) | GAAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21927159 | 0.72 | AURKA (0.47) | PDE3BPDE3AGAAALDH1A1KDM4E | |
| SCHEMBL22425308 | 0.72 | MAPT (0.63) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL22424889 | 0.72 | MAPT (0.60) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL13293335 | 0.71 | GAA (0.48) | PDE3BPDE3AGAAPKMALDH1A1 | |
| SCHEMBL92048 | 0.71 | GAA (0.53) | PDE3BPDE3AGAAPKMKDM4E | |
| SCHEMBL3348374 | 0.71 | GAA (0.48) | PDE3BPDE3AGAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026474-B1 | COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR | Wella Aktiengesellschaft (DE) | 1983-06-08 | — | — | EP | claimed |
| EP-0026474-A1 | Composition and process for oxidative dyeing of hair | Wella Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | claimed |
| WO-1981000811-A1 | MEANS AND PROCESS ALLOWING HAIR COLORATION BY OXIDATION | WELLA AG (DE) | 1981-04-02 | — | — | WO | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
| US-10095144-B2 | Toner and method for manufacturing the same | CANON KABUSHIKI KAISHA (JP) | 2018-10-09 | — | — | US | disclosed |
| US-9996018-B2 | Toner and method for manufacturing the same | CANON KABUSHIKI KAISHA (JP) | 2018-06-12 | — | — | US | disclosed |
| US-9996018-B2 | Toner and method for manufacturing the same | CANON KABUSHIKI KAISHA (JP) | 2018-06-12 | — | — | US | disclosed |
| US-9873693-B2 | Methods of treatment using pyridinonyl PDK1 inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| EP-2782567-B1 | DISUBSTITUTED BETA-LACTONES AS INHIBITORS OF N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) | UNIV CALIFORNIA (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20170060015-A1 | TONER AND METHOD FOR MANUFACTURING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2017-03-02 | — | — | US | disclosed |
| US-20040107518-A1 | Hetero-anellated ortho-aminophenols and their use as dye components | CLARIANT FINANCE (BVI) LIMITED (BR) | 2004-06-10 | — | — | US | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1335905-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | Clariant International Ltd. (CH) | 2003-08-20 | — | — | EP | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |
| WO-2002038549-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | CLARIANT FINANCE (BVI) LTD. (GB) | 2002-05-16 | — | — | WO | disclosed |
| US-4620850-A | HYDROXYBENZOLFURANONE | WELLA AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0026474-B1 | COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR | Wella Aktiengesellschaft (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0026474-A1 | Composition and process for oxidative dyeing of hair | Wella Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |
| WO-1981000811-A1 | MEANS AND PROCESS ALLOWING HAIR COLORATION BY OXIDATION | WELLA AG (DE) | 1981-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | THRA, THRB, TSHR | PDE3B 3920/4885PDE3A 3467/4885GAA 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.