SCHEMBL92048

SCHEMBL92048

Nc1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.53
PKM P14618 2/20 0.53
GRIA1 P42261 4/20 0.48
CACNG8 Q8WXS5 4/20 0.48
PARP1 P09874 2/20 0.48
PDE3B Q13370 2/20 0.48
PDE3A Q14432 2/20 0.48
MAPKAPK2 P49137 1/20 0.46
RPS6KA3 P51812 1/20 0.46
CSNK2A1 P68400 1/20 0.46
PLK3 Q9H4B4 1/20 0.46
KDM4E B2RXH2 3/20 0.44
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
CYP2A6 P11509 1/20 0.42
KEAP1 Q14145 1/20 0.42
AR P10275 2/20 0.42
NGFR P08138 1/20 0.42
MAPK1 P28482 2/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558701 1.00 GAA (0.53) GAAPKMGRIA1CACNG8PARP1
Hydrochloric Acid SCHEMBL27948201 0.98 GAA (0.57) GAAPKMGRIA1CACNG8PARP1
Water SCHEMBL11163622 0.98 GAA (0.52) GAAPKMGRIA1CACNG8PARP1
SCHEMBL2125814 0.86 PARP1 (0.59) GRIA1PARP1MAPKAPK2RPS6KA3CSNK2A1
SCHEMBL4610600 0.79 PARP1 (0.62) PARP1PDE3AMAPKAPK2RPS6KA3CSNK2A1
SCHEMBL30586623 0.79 PARP1 (0.67) PARP1KDM4ECA12CA9AR
SCHEMBL5368114 0.79 PARP1 (0.67) PARP1KDM4ECA12CA9AR
SCHEMBL980513 0.78 GRIA1 (0.60) GAAPKMGRIA1CACNG8PDE3B
SCHEMBL31074001 0.78 MAPT (0.50) GAAPKMGRIA1CACNG8PARP1
SCHEMBL12322303 0.77 GRIA1 (0.58) GAAPKMGRIA1CACNG8PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 744 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119318874-B Preparation method of energy-saving composite desulfurizing agent 淄博凯美可工贸有限公司 2025-04-15 CN claimed
CN-113512720-B Copper precipitation pretreatment liquid and pretreatment method thereof 广东硕成科技股份有限公司 2022-06-17 CN claimed
CN-113512720-A Copper precipitation pretreatment liquid and pretreatment method thereof 广东硕成科技有限公司 2021-10-19 CN claimed
CN-110777381-A Composition for TiN hardmask removal and etch residue cleaning 弗萨姆材料美国有限责任公司 2020-02-11 CN claimed
US-20200035485-A1 Composition For TiN Hard Mask Removal And Etch Residue Cleaning VERSUM MATERIALS US, LLC (US) 2020-01-30 US claimed
EP-3599634-A1 COMPOSITION FOR TITANIUM NITRIDE HARD MASK REMOVAL AND ETCH RESIDUE CLEANING Versum Materials US, LLC (US) 2020-01-29 EP claimed
CN-110183385-A A method of improving 5-acetoacetamido benzimidazolone purity 山东汇海医药化工有限公司 2019-08-30 CN claimed
CN-110128350-A A method of improving 5-acetoacetamido benzimidazolone quality 山东汇海医药化工有限公司 2019-08-16 CN claimed
CN-109868008-A A kind of laser labelling ink 刘应良 2019-06-11 CN claimed
CN-109748877-A A kind of preparation method of 5-acetoacetamido benzimidazolone 济南大学 2019-05-14 CN claimed
CN-101621927-A Diaminopyrimidines as fungicides BAYER CROPSCIENCE AG 2010-01-06 CN claimed
EP-2129222-A1 DIAMINOPYRIMIDINES AS FUNGICIDES Bayer CropScience AG (DE) 2009-12-09 EP claimed
WO-2009135925-A1 SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2009-11-12 WO claimed
EP-2116547-A1 Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands Laboratorios Del. Dr. Esteve, S.A. (ES) 2009-11-11 EP claimed
WO-2009115267-A2 DIAMINOPYRIMIDINES AS PLANT PROTECTION AGENTS BAYER CROPSCIENCE AG (DE) 2009-09-24 WO claimed
WO-2008107096-A1 DIAMINOPYRIMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-12 WO claimed
WO-2006058338-A2 4 - PIPERIDINECARBOXAMIDE DERIVATIVES AS MODULATORS OF VANILLOID VR1 RECEPTOR JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-01 WO claimed
US-20060116368-A1 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-01 US claimed
EP-0648748-B1 Process for the preparation of 5-acetoacetylaminobenzimidazolon-2 HOECHST AG (DE) 1997-05-02 EP claimed
US-5476948-A Preparation of 5-acetoacetylamino-2-benzimidazolone HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060116368-A1 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor VDAC1, TRPV1, HVCN1 GAA 4677/4885PKM 3255/4885GRIA1 214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.