Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.30 |
| ▸ | MICA | Q29983 | 1/20 | 0.30 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295467 | 0.83 | TACR1 (0.33) | IDO1TDO2RXRARXRBRXRG | |
| SCHEMBL15792035 | 0.83 | RXRA (0.32) | IDO1TDO2RXRARXRBRXRG | |
| SCHEMBL31749745 | 0.83 | TACR1 (0.33) | IDO1TDO2RXRARXRBRXRG | |
| SCHEMBL2183595 | 0.80 | CES2 (0.37) | IDO1TDO2RXRARXRBRXRG | |
| SCHEMBL7356689 | 0.79 | RXRA (0.33) | RXRARXRBRXRGCES2GSK3B | |
| SCHEMBL8127537 | 0.78 | PDE2A (0.35) | IDO1TDO2RXRARXRBRXRG | |
| SCHEMBL28390698 | 0.78 | CES2 (0.39) | IDO1TDO2CES2 | |
| SCHEMBL9693899 | 0.75 | CES2 (0.42) | IDO1RXRARXRBRXRGCES2 | |
| SCHEMBL4461544 | 0.75 | CES2 (0.48) | IDO1RXRARXRBRXRGCES2 | |
| SCHEMBL25429733 | 0.75 | RXRA (0.35) | IDO1TDO2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041296-B | Aminoacetamides containing benzooxy alicyclic structures and uses thereof | 上海璃道医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |