Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | MPL | P40238 | 3/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27641105 | 0.84 | P2RX7 (0.66) | P2RX7IDO1TDO2MPLEPHX2 | |
| SCHEMBL63989 | 0.81 | IDO1 (0.51) | P2RX7IDO1TDO2MPLACP3 | |
| SCHEMBL9242031 | 0.80 | P2RX7 (0.50) | P2RX7IDO1TDO2KIF11ACP3 | |
| SCHEMBL30705308 | 0.80 | P2RX7 (0.50) | P2RX7IDO1TDO2KIF11ACP3 | |
| SCHEMBL20551075 | 0.80 | IDO1 (0.44) | P2RX7IDO1TDO2MPLACP3 | |
| SCHEMBL24801386 | 0.79 | IDO1 (0.54) | P2RX7IDO1TDO2MPLACP3 | |
| SCHEMBL12009462 | 0.79 | P2RX7 (0.50) | P2RX7IDO1TDO2MPLEPHX2 | |
| Fluoride SCHEMBL28044840 | 0.79 | IDO1 (0.50) | P2RX7IDO1TDO2MPLACP3 | |
| SCHEMBL7601747 | 0.77 | MPL (0.46) | P2RX7IDO1TDO2MPLAXL | |
| SCHEMBL14120782 | 0.76 | IDO1 (0.51) | P2RX7IDO1TDO2MPLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041296-B | Aminoacetamides containing benzooxy alicyclic structures and uses thereof | 上海璃道医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |