Fluoride

Fluoride

SCHEMBL28044840

F.Fc1c(C(F)F)cccc1C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
TDO2 P48775 1/20 0.50
P2RX7 Q99572 1/20 0.42
MPL P40238 3/20 0.37
SOS1 Q07889 4/20 0.36
ACP3 P15309 1/20 0.35
TRPA1 O75762 1/20 0.35
PDE2A O00408 1/20 0.34
CTSS P25774 1/20 0.34
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KRAS P01116 2/20 0.33
CCR1 P32246 1/20 0.33
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
HCAR1 Q9BXC0 1/20 0.32
NOTUM Q6P988 1/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63989 0.98 IDO1 (0.51) IDO1TDO2P2RX7MPLSOS1
SCHEMBL24801386 0.79 IDO1 (0.54) IDO1TDO2P2RX7MPLACP3
SCHEMBL30705305 0.79 P2RX7 (0.50) IDO1TDO2P2RX7MPLACP3
SCHEMBL23344942 0.79 CA2 (0.41) IDO1TDO2P2RX7SOS1KRAS
SCHEMBL12009462 0.79 P2RX7 (0.50) IDO1TDO2P2RX7MPLTRPA1
SCHEMBL7197239 0.78 PDE2A (0.51) IDO1TDO2TRPA1PDE2A
SCHEMBL10546400 0.78 ACP3 (0.47) IDO1TDO2P2RX7ACP3TRPA1
SCHEMBL7601747 0.77 MPL (0.46) IDO1TDO2P2RX7MPLCTSS
SCHEMBL25019477 0.76 IDO1 (0.47) IDO1TDO2P2RX7MPLSOS1
SCHEMBL24988934 0.76 IDO1 (0.47) IDO1TDO2P2RX7MPLSOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175713-A Perfluoropolyether silane, preparation method of perfluoropolyether silane and application of perfluoropolyether silane BEIJING LAINUOTAIKE SCIENCE & TECHNOLOGY CO LTD 2015-12-23 CN claimed
CN-105175713-B Perfluoropolyether silanes and preparation method and application 北京莱诺泰克科技有限公司 2017-06-06 CN disclosed
CN-105175713-A Perfluoropolyether silane, preparation method of perfluoropolyether silane and application of perfluoropolyether silane BEIJING LAINUOTAIKE SCIENCE & TECHNOLOGY CO LTD 2015-12-23 CN disclosed