Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 2/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705387 | 0.82 | KMT2A (0.42) | KMT2AMEN1LMNAMAPTRAB9A | |
| SCHEMBL3681186 | 0.72 | TDP1 (0.37) | LMNAALDH1A1 | |
| SCHEMBL14233363 | 0.68 | TAS2R14 (0.51) | TAS2R14KCNJ5KCNJ3GALR2GALR1 | |
| SCHEMBL22838167 | 0.68 | TAS2R14 (0.51) | TAS2R14KCNJ5KCNJ3GALR2GALR1 | |
| SCHEMBL18884385 | 0.68 | TAS2R14 (0.51) | TAS2R14KCNJ5KCNJ3GALR2GALR1 | |
| SCHEMBL21258954 | 0.66 | TAS2R14 (0.66) | TAS2R14KCNJ5KCNJ3GALR2GALR1 | |
| Hydrochloric Acid SCHEMBL14150624 | 0.66 | TAS2R14 (0.50) | TAS2R14KCNJ5KCNJ3GALR2GALR1 | |
| SCHEMBL4106286 | 0.65 | MAPT (0.65) | TAS2R14KCNJ5KCNJ3GRM4EPHX2 | |
| SCHEMBL18154972 | 0.64 | TAS2R14 (0.48) | TAS2R14KCNJ5KCNJ3GALR2GALR1 | |
| SCHEMBL15755676 | 0.64 | GRM4 (0.49) | TAS2R14KCNJ5KCNJ3GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098765-A | Heterocyclic derivatives as Janus kinase inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | disclosed |