Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705391 | 0.82 | TAS2R14 (0.40) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL3681186 | 0.76 | TDP1 (0.37) | MAPK1CYP2C19IDO1TSHRLMNA | |
| SCHEMBL28066685 | 0.72 | ADRB1 (0.45) | KMT2AMEN1MAPTNPC1CYP2C19 | |
| SCHEMBL6364424 | 0.70 | HTT (0.57) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL7055546 | 0.69 | NPC1 (0.58) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL27366559 | 0.68 | SIGMAR1 (0.52) | KMT2AMEN1MAPTPOLBIDO1 | |
| SCHEMBL8326648 | 0.67 | KMT2A (0.60) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL1085867 | 0.67 | MEN1 (0.71) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL28470521 | 0.67 | SMN1; SMN2 (0.58) | POLBHTTNPC1CYP2C19RAB9A | |
| SCHEMBL1999229 | 0.66 | GAA (0.36) | KMT2AMEN1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098765-A | Heterocyclic derivatives as Janus kinase inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | disclosed |