Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405639 | 0.79 | RAB9A (0.41) | TSHRRAB9AL3MBTL1NOTUMPARP1 | |
| SCHEMBL21055089 | 0.78 | TSHR (0.40) | TSHRRAB9AL3MBTL1NOTUMPARP1 | |
| SCHEMBL31056496 | 0.78 | NR4A1 (0.46) | TSHRRAB9AL3MBTL1NOTUMALB | |
| SCHEMBL4048895 | 0.78 | NOTUM (0.42) | TSHRRAB9AL3MBTL1NOTUMPARP1 | |
| SCHEMBL15971447 | 0.78 | NOTUM (0.41) | TSHRRAB9AL3MBTL1NOTUMCCR2 | |
| Hydrochloric Acid SCHEMBL31056543 | 0.76 | NR4A1 (0.44) | TSHRRAB9AL3MBTL1NOTUMALB | |
| SCHEMBL18542876 | 0.76 | FABP4 (0.37) | FABP4TSHRRAB9AL3MBTL1NOTUM | |
| SCHEMBL24110482 | 0.76 | FABP4 (0.39) | FABP4L3MBTL1NOTUMPARP1CCR2 | |
| SCHEMBL16339898 | 0.76 | ACLY (0.54) | FABP4L3MBTL1NOTUMACLYBCHE | |
| SCHEMBL30705764 | 0.76 | FABP4 (0.36) | FABP4NOTUMCES2CES1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |