Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 3/20 | 0.42 |
| ▸ | PNP | P00491 | 3/20 | 0.42 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743926 | 0.78 | GRIA1 (0.62) | ALDH1A1XDHPNPHPRT1GRIA1 | |
| SCHEMBL21977265 | 0.78 | PDE7A (0.58) | PDE7APDE7BALDH1A1PMP22PNP | |
| SCHEMBL22039142 | 0.78 | PDE7A (0.44) | PDE7APDE7BALDH1A1XDHPNP | |
| SCHEMBL22039136 | 0.77 | HCAR1 (0.45) | PDE7APDE7BALDH1A1KDM4EXDH | |
| SCHEMBL29903916 | 0.76 | PDE7A (0.42) | PDE7APDE7BKDM4EPMP22PNP | |
| SCHEMBL12432260 | 0.74 | XDH (0.55) | HSD17B10ALDH1A1KDM4ELMNAGLA | |
| SCHEMBL13065905 | 0.71 | PNP (0.74) | PNP | |
| SCHEMBL13022847 | 0.71 | PNP (0.74) | PNP | |
| SCHEMBL22560002 | 0.70 | PIK3CD (0.45) | ALDH1A1KDM4EPNPTSHRUSP2 | |
| SCHEMBL19286496 | 0.70 | XDH (0.46) | HSD17B10ALDH1A1KDM4ELMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756805-A | Pteridinone derivatives as RSK inhibitors and their use | 华东师范大学 | 2024-03-26 | — | — | CN | disclosed |
| WO-2024008097-A1 | COMPOUND FOR TARGETED DEGRADATION OF CDK PROTEIN AND USE THEREOF | 华东理工大学 | 2024-01-11 | — | — | WO | disclosed |