Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.44 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.43 |
| ▸ | PNP | P00491 | 5/20 | 0.42 |
| ▸ | DHFR | P00374 | 3/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22039136 | 0.99 | HCAR1 (0.45) | PDE7APDE7BHCAR1PNPDHFR | |
| SCHEMBL21977265 | 0.83 | PDE7A (0.58) | PDE7APDE7BPNPDHFRALDH1A1 | |
| SCHEMBL29903916 | 0.81 | PDE7A (0.42) | PDE7APDE7BHCAR1PNPDHFR | |
| SCHEMBL30707754 | 0.78 | PDE7A (0.42) | PDE7APDE7BPNPXDHUSP2 | |
| SCHEMBL12958955 | 0.73 | XDH (0.49) | PNPDHFRXDHALDH1A1 | |
| SCHEMBL22560002 | 0.72 | PIK3CD (0.45) | HCAR1PNPRGS12USP2ALDH1A1 | |
| SCHEMBL29903897 | 0.72 | PDE7A (0.37) | PDE7APDE7BPNPRGS12USP2 | |
| SCHEMBL9366143 | 0.72 | PNP (0.49) | PNP | |
| SCHEMBL9366148 | 0.72 | PNP (0.49) | PNP | |
| SCHEMBL14743926 | 0.71 | GRIA1 (0.62) | PNPXDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | TOHOKU UNIVERSITY (JP) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | SQSTM1, BECN1, ATG7 | PDE7A 4164/4885PDE7B 4241/4885HCAR1 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.