Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139928 | 1.00 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11373831 | 0.79 | LMNA (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11369775 | 0.79 | KDM4E (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL24813004 | 0.77 | AKR1C3 (0.51) | LMNAL3MBTL1ALDH1A1TP53ALOX15 | |
| SCHEMBL30708130 | 0.77 | AKR1C3 (0.51) | LMNAL3MBTL1ALDH1A1TP53ALOX15 | |
| SCHEMBL369096 | 0.74 | KMT2A (0.52) | LMNAL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL17102820 | 0.73 | KMT2A (0.57) | LMNAL3MBTL1ALDH1A1NPSR1KDM4E | |
| SCHEMBL3926759 | 0.73 | MGLL (0.34) | LMNAL3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL30275171 | 0.70 | L3MBTL1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20280298 | 0.69 | LMNA (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |