SCHEMBL30708249

SCHEMBL30708249

O=C1C(c2cccc(O)c2)=C(c2cccc(O)c2)C(=O)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.59
ESR2 Q92731 4/20 0.59
HSD17B1 P14061 5/20 0.50
HSD17B2 P37059 5/20 0.50
TUBB4A P04350 1/20 0.50
TUBB P07437 1/20 0.50
TUBA3C P0DPH7 1/20 0.50
AR P10275 1/20 0.50
TUBA1B P68363 1/20 0.50
TUBA4A P68366 1/20 0.50
TUBB4B P68371 1/20 0.50
TUBB3 Q13509 1/20 0.50
TUBB2A Q13885 1/20 0.50
TUBB8 Q3ZCM7 1/20 0.50
TUBA3E Q6PEY2 1/20 0.50
TUBA1A Q71U36 1/20 0.50
TUBA1C Q9BQE3 1/20 0.50
TUBB6 Q9BUF5 1/20 0.50
TUBB2B Q9BVA1 1/20 0.50
TUBB1 Q9H4B7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849472 0.82 ESR1 (0.47) ESR1ESR2HSD17B1HSD17B2CYP3A4
SCHEMBL22182158 0.81 TDP2 (0.51) ESR1ESR2HSD17B1HSD17B2TUBB4A
SCHEMBL4779452 0.78 HSD17B1 (0.64) ESR1ESR2HSD17B1HSD17B2CYP3A4
SCHEMBL24849449 0.77 BACE1 (0.68) ESR1ESR2HSD17B1HSD17B2TUBB4A
SCHEMBL3680161 0.76 HSD17B1 (0.61) ESR1ESR2HSD17B1HSD17B2CYP3A4
SCHEMBL5497788 0.75 MAPT (0.65) ESR1ESR2P2RX7APAF1TDP2
SCHEMBL3929813 0.74 ESR2 (1.00) ESR1ESR2P2RX7
SCHEMBL5050883 0.74 HSD17B1 (0.58) ESR1ESR2HSD17B1HSD17B2CYP3A4
SCHEMBL17051267 0.74 HSD17B1 (0.58) ESR1ESR2HSD17B1HSD17B2CYP3A4
SCHEMBL3440709 0.73 HSD17B1 (0.52) ESR1ESR2HSD17B1HSD17B2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117561108-A Method for separating electroactive species from electrochemical gases 沃道克斯公司 2024-02-13 CN disclosed