Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 10/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651426 | 0.98 | HSD17B1 (0.56) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL4779452 | 0.95 | HSD17B1 (0.64) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL3680161 | 0.93 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL13612222 | 0.91 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL28235602 | 0.91 | HSD17B1 (0.74) | HSD17B1HSD17B2CYP3A4CYP2C9ABL1 | |
| SCHEMBL17051267 | 0.91 | HSD17B1 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL9396344 | 0.90 | ALOX5 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL11601339 | 0.90 | ALOX5 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL15419773 | 0.89 | HSD17B1 (0.56) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 | |
| SCHEMBL8450704 | 0.89 | ALOX5 (0.63) | HSD17B1HSD17B2CYP3A4CYP2C9ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1164227-A | Dibenzimidazole derivatives | HOFFMANN LA ROCHE (CH) | 1997-11-05 | — | — | CN | claimed |
| CN-109943349-B | Liquid-crystalline medium with homeotropic alignment | 默克专利股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117050102-A | Fluorene-containing aromatic amine derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-109825312-B | Liquid-crystalline medium with homeotropic alignment | 默克专利股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20080075950-A1 | Electron-Conjugated Organic Silane Compound, Functional Organic Thin Film And Production Method Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-03-27 | — | — | US | disclosed |
| CN-1993371-A | Organosilane compounds of pi-electron conjugated system, functional organic thin films, and processes for production of both | SHARP KK (JP) | 2007-07-04 | — | — | CN | disclosed |
| EP-1408986-A4 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-1408986-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002089738-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2002-11-14 | — | — | WO | disclosed |
| CN-1164227-A | Dibenzimidazole derivatives | HOFFMANN LA ROCHE (CH) | 1997-11-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080075950-A1 | Electron-Conjugated Organic Silane Compound, Functional Organic Thin Film And Production Method Thereof | AOX1, QSOX1, AOC3 | HSD17B1 221/4885HSD17B2 297/4885CYP3A4 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.