Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | TERT | O14746 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2569512 | 0.94 | AKT2 (0.31) | AKT2SMN1; SMN2TERTRAB9AKDM4E | |
| Trifluoroacetic Acid SCHEMBL2569510 | 0.94 | AKT2 (0.31) | AKT2SMN1; SMN2TERTRAB9AKDM4E | |
| SCHEMBL479884 | 0.92 | POLB (0.41) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL3156332 | 0.92 | POLB (0.41) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2567052 | 0.90 | RXFP1 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL480698 | 0.90 | RXFP1 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL30708658 | 0.88 | SMN1; SMN2 (0.35) | AKT2SMN1; SMN2TERTRAB9ANPC1 | |
| SCHEMBL479373 | 0.85 | POLB (0.42) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL3149311 | 0.85 | POLB (0.42) | SMN1; SMN2RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2571997 | 0.83 | RXFP1 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | MMP1, COL1A1, SMAD3 | AKT2 3227/4885SMN1; SMN2 2525/4885TERT 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.