Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2572729 | 0.94 | BACE1 (0.33) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| Trifluoroacetic Acid SCHEMBL2572727 | 0.94 | BACE1 (0.33) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| SCHEMBL2571915 | 0.91 | POLB (0.43) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| SCHEMBL2121862 | 0.91 | POLB (0.43) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| SCHEMBL30708644 | 0.88 | AKT2 (0.34) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| SCHEMBL2564367 | 0.83 | KMT2A (0.37) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| SCHEMBL2564369 | 0.83 | KMT2A (0.37) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| SCHEMBL224167 | 0.83 | BACE1 (0.36) | SMN1; SMN2TOP2BLMNABACE1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2569510 | 0.83 | AKT2 (0.31) | SMN1; SMN2NPC1POLBRAB9ATOP2B | |
| Trifluoroacetic Acid SCHEMBL2569512 | 0.83 | AKT2 (0.31) | SMN1; SMN2NPC1POLBRAB9ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | MMP1, COL1A1, SMAD3 | SMN1; SMN2 2525/4885NPC1 1224/4885POLB 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.