Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NNMT | P40261 | 3/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 6/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25419641 | 0.98 | LMNA (0.54) | LMNANNMTF7F3SARM1 | |
| SCHEMBL557159 | 0.83 | ALKBH2 (0.47) | LMNAKITDDR1PDE4BPDE4D | |
| SCHEMBL3608804 | 0.81 | KIT (0.39) | LMNAKITDDR1PDE4BPDE4D | |
| SCHEMBL18825814 | 0.78 | NTRK1 (0.47) | KITDDR1NTRK1DDR2 | |
| SCHEMBL21855118 | 0.75 | KIT (0.50) | KITDDR1DDR2 | |
| SCHEMBL3611630 | 0.74 | MAP4K4 (0.46) | LMNASMN1; SMN2KITDDR1MAP4K4 | |
| SCHEMBL2448509 | 0.74 | ABL1 (0.41) | KITDDR1PDE4BPDE4DNTRK1 | |
| SCHEMBL6886297 | 0.72 | DYRK1A (0.45) | LMNANNMTSMN1; SMN2PDE4BMAP4K4 | |
| SCHEMBL7067259 | 0.72 | TP53 (0.43) | SMN1; SMN2KITDDR1NTRK1 | |
| SCHEMBL20556098 | 0.72 | LMNA (0.62) | LMNASMN1; SMN2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120442-A | Tricyclic compounds useful for treating cancer, autoimmune disorders, and inflammatory disorders | 薛定谔公司 | 2023-11-24 | — | — | CN | disclosed |