SCHEMBL30709609

SCHEMBL30709609

CCc1ccc([C@@H](O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.46
ALDH1A1 P00352 7/20 0.44
TSHR P16473 6/20 0.44
MAPT P10636 5/20 0.44
LMNA P02545 4/20 0.44
GAA P10253 3/20 0.44
ALOX15 P16050 3/20 0.44
KDM4E B2RXH2 3/20 0.44
PKM P14618 1/20 0.44
ALOX12 P18054 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA2 P00918 4/20 0.41
CA1 P00915 2/20 0.41
CYP1A2 P05177 4/20 0.40
MAPK1 P28482 4/20 0.40
CYP3A4 P08684 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ATM Q13315 3/20 0.40
CYP2C9 P11712 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30709668 0.81 CA2 (0.53) HSPA5ALDH1A1TSHRMAPTLMNA
SCHEMBL30709713 0.80 TSHR (0.50) ALDH1A1TSHRMAPTLMNAGAA
SCHEMBL9136246 0.80 TSHR (0.50) ALDH1A1TSHRMAPTLMNAGAA
SCHEMBL30709677 0.77 CA2 (0.58) ALDH1A1TSHRMAPTLMNAGAA
SCHEMBL10512771 0.76 HSPA5 (0.56) HSPA5ALDH1A1TSHRMAPTLMNA
SCHEMBL30641457 0.75 ALDH1A1 (0.51) ALDH1A1TSHRMAPTLMNAGAA
SCHEMBL39434 0.74 HSPA5 (0.74) HSPA5ALDH1A1TSHRMAPTLMNA
SCHEMBL18982775 0.72 CA2 (0.50) HSPA5ALDH1A1TSHRMAPTLMNA
SCHEMBL6899388 0.71 TP53 (0.54) ALDH1A1TSHRLMNAKDM4ECA2
Hydrochloric Acid SCHEMBL6039741 0.71 HSPA5 (0.69) HSPA5ALDH1A1TSHRMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903773-A Preparation method of polymer composite copper catalytic material and application of polymer composite copper catalytic material in synthesis of chiral gem diaryl borate 湖北工程学院 2023-10-20 CN disclosed